Glass Toxicity Testing
The Center for Risk Analysis & Management at the University of South Florida, College of Public Health has tested 52 laboratory subjects (rats), through invasive and non-invasive procedures. The 32 day animal research study, believed to be the first of its kind regarding vitrified product material, is complete.
As part of their daily diet each animal was fed with a specific dosage of powdered glass in saline solution. Following a phase one evaluation of 12 rats, the remaining 40 subjects were divided into three sets of 10, with a 10 animal control/baseline group. Glass was fed at dosage concentrations of 1,3, and 6 gr/l00ml (low, mid, high). At the high concentration this equates to nearly 26 gr/ day for a 70kg adult. Taking the historical ingestion cutoff utilized by EPA of 100 mg/day for an adult, the study ‘high’ test dose is over 250 times that indicated by the regulatory framework (Risk Assessment Guidance for Superfiind and Exposure Factors Handbook).
Yet, clinical and pathological observations during the study show no unique or suspect animal behavior. Blood metals were statistically unchanged. What statistical evidence appeared in constituents of interest (As and Cu) is minor when considering the huge difference in dosages. A comparison of EPA risk-based concentration data used in Comprehensive Environmental Response, Compensation, and Liability Act activities shows all glass product metals at lower values except for As and Cr, which are both in the oxidized and bound chemically stable state in the glass. Contrasting soil metals concentrations in the United States with that in the vitrified glass showed all the metals were within the ranges except Cr, Mg, Se and Sn; and none of these were statistically increased in the blood, liver or kidney tissues analyzed.
The University of South Florida’s researchers summarized their research conclusions by observing that: "....one finds no evidence of disease manifestation in any of the 52 test animals." and
… one can conclude that there is no evidence of adverse health effects at an ingested dosage of 370 mg vitreous material/kg body weight (25.9 g/70 kg adult per day) over a 32 day period of time."
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